Lab On A Chip
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Recent papers in Lab On A Chip
Chain reactions are characterized by initiation, propagation and termination, are stochastic at microscopic scales and underlie vital chemical (e.g. combustion engines), nuclear and biotechnological (e.g. polymerase chain reaction)... more
The human gut is over a meter in length, liquid residence times span several hours. Recapitulating the human gut microbiome "on chip" holds promise to revolutionize therapeutic strategies for a variety of diseases, as well as... more
Microfluidics-based biochip applications have been increased abruptly in multiple fields because of the advantages in manifolds, which include decreased test sample utilization and reagent consumption with numerous purposes and highly... more
We develop a quantitative lateral flow assay (LFA) device that is able to measure the tear level of brain derived neurotrophic factor (BDNF). The device shows great potential to serve as an ideal platform for early detection of glaucoma.
Circulating tumor cells (CTCs) play an essential role in the metastasis of tumors, and thus can serve as a valuable prognostic factor for malignant diseases. As a result, the ability to isolate and characterize CTCs is essential. This... more
Fabrication conditions for high-aspect-ratio MNs by the photopolymerization of PEGDA were investigated. The influence of prepolymer molecular weight and the degree of UV absorption by the photoinitiator (PI) were studied to optimize the... more
This systematic review aimed to analyze the development and functionality of microfluidic concentration gradient generators (CGGs) for toxicological evaluation of different biological organisms. We searched articles using the keywords:... more
The intricate microenvironment in which malignant cells reside is essential for the progression of tumor growth. Both the physical and biochemical features of the tumor microenvironment (TME) play a critical role in promoting the... more
Detection of conformational changes in biomolecular assemblies provides critical information into biological and self-assembly processes. State-of-the-art in situ biomolecular conformation detection techniques rely on fluorescent labels... more
On-chip microwave calibrations are used to characterize the electrical-double layer response for saline solutions in microfluidic channels over an extremely broad frequency range.
Integrins are key players in platelet adhesion and aggregation.
To improve our understanding of how the central nervous system functions, we report the development of an integrated chip for studying the effects of the neurotransmitters on adult rat hippocampal progenitor cell neurospheroids.
This study expands the utilization of an ex vivo dual flow microfluidic device to create a model of leaky gut using bacterial collagenase.
Although fused deposition modeling (FDM) is of great interest for the cost-effective manufacture of polymer parts with complex customized geometries, it currently provides insufficient mechanical integrity for the production of high... more